Iowa is a state in the Midwestern United States.
Iowa was the location of the Burton School for the Blind where Mary Ingalls was sent to coup with her blindness and where she met Adam Kendall, her future husband. (Episode 422: I'll Be Waving As You Drive Away (Part 2))
Charles Ingalls and his remaining family moved to a town known as Burr Oak in Iowa after work in Walnut Grove went dry. (Episode 901: Times Are Changing (Part 1))